Main
Kavee Limbutara, MD
Nephrologist
- A physician-scientist with board certified in Internal Medicine and Nephrology.
- Experienced in Omics techniques including Proteomics and Transcriptomics (both experimental and computational works).
- Strong background in basic science, clinical science, and information technology.
- My personal goal is to integrate biotechnology, information technology, and clinical knowledge to deliver Precision Medicine.
Education
Chulalongkorn University
Doctor of Medicine (1st Class Honours, GPAX 3.87)
Bangkok, Thailand
2010
Hatyai Hospital
Diploma of The Thai Board of Internal Medicine
Songkhla, Thailand
2014
Research: Prevalence of hypokalemia in adult with dengue virus infection.
King Chulalongkorn Memorial Hospital
Diploma of The Thai Board of Nephrology
Bangkok, Thailand
2016
Research: Quantitative Phosphosproteomic Analysis of Rat Renal Cortical Tubules in Response to Phospholipase A2 from Russell’s Viper Venom.
Professional Experience
General Practitioner
Hatyai Hospital
Songkhla, Thailand
2010-2011
General Practitioner
Trakanphuetpol Hospital
Ubon Ratchathani , Thailand
Nov 2010 - Jan 2011
Internal Medicine Resident
Hatyai Hospital
Songkhla, Thailand
2011 - 2014
Nephrology Fellow
King Chulalongkorn Memorial Hospital
Bangkok, Thailand
2014 - 2016
Nephrologist
King Chulalongkorn Memorial Hospital
Bangkok, Thailand
2016 - 2017
Postdoctoral Fellow
Epithelial Systems Biology Laboratory, Systems Biology Center, NHLBI, NIH
Bethesda, MD, USA
2018 - 2019
- Mass spectrometry-based proteomics.
- Kidney tubule microdissection.
- Developed shiny-based web applications.
Nephrologist
Sukumvit Hospital
Bangkok, Thailand
June 2020 - July 2023
Nephrologist
Faculty of Medicine Vajira Hospital, Navamindradhiraj University
Bangkok, Thailand
August 2023 - Present
Selected Publications
Signaling mechanisms in renal compensatory hypertrophy revealed by multi-omics.
Nat Commun. 2023 Jun 16; 14(1):3481.
N/A
2023
Kikuchi H, Chou CL, Yang CR, Chen L, Jung HJ, Park E, Limbutara K, Carter B, Yang ZH, Kun JF, Remaley AT, Knepper MA
Candida Administration in Bilateral Nephrectomy Mice Elevates Serum (1→3)-β-D-glucan That Enhances Systemic Inflammation Through Energy Augmentation in Macrophages.
Int J Mol Sci. 2021 May 10; 22(9):.
N/A
2021
Issara-Amphorn J, Dang CP, Saisorn W, Limbutara K, Leelahavanichkul A
Protein kinase A catalytic-α and catalytic-β proteins have nonredundant regulatory functions.
Am J Physiol Renal Physiol. 2020 Nov 1; 319(5):F848-F862.
N/A
2020
Raghuram V, Salhadar K, Limbutara K, Park E, Yang CR, Knepper MA
Quantitative Proteomics of All 14 Renal Tubule Segments in Rat.
J Am Soc Nephrol. 2020 Jun; 31(6):1255-1266.
N/A
2020
Limbutara K, Chou CL, Knepper MA
Phosphoproteomic Identification of Vasopressin/cAMP/Protein Kinase A-Dependent Signaling in Kidney.
Mol Pharmacol. 2021 May; 99(5):358-369.
N/A
2021
Salhadar K, Matthews A, Raghuram V, Limbutara K, Yang CR, Datta A, Chou CL, Knepper MA
PKA-independent vasopressin signaling in renal collecting duct.
FASEB J. 2020 May; 34(5):6129-6146.
N/A
2020
Datta A, Yang CR, Limbutara K, Chou CL, Rinschen MM, Raghuram V, Knepper MA
RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus.
Kidney Int. 2019 Aug; 96(2):363-377.
N/A
2019
Sung CC, Chen L, Limbutara K, Jung HJ, Gilmer GG, Yang CR, Lin SH, Khositseth S, Chou CL, Knepper MA
Phosphorylation Changes in Response to Kinase Inhibitor H89 in PKA-Null Cells.
Sci Rep. 2019 Feb 26; 9(1):2814.
N/A
2019
Limbutara K, Kelleher A, Yang CR, Raghuram V, Knepper MA
From Molecules to Mechanisms: Functional Proteomics and Its Application to Renal Tubule Physiology.
Physiol Rev. 2018 Oct 1; 98(4):2571-2606.
N/A
2018
Rinschen MM, Limbutara K, Knepper MA, Payne DM, Pisitkun T
RNA sequencing of kidney distal tubule cells reveals multiple mediators of chronic aldosterone action.
Physiol Genomics. 2018 May 1; 50(5):343-354.
N/A
2018
Poulsen SB, Limbutara K, Fenton RA, Pisitkun T, Christensen BM
Proteomic analysis of the kidney filtration barrier–Problems and perspectives.
Proteomics Clin Appl. 2015 Dec; 9(11-12):1053-68.
N/A
2015
Rinschen MM, Benzing T, Limbutara K, Pisitkun T
Posters
Quantitative Phosphoproteomic Analysis of Rat Renal Cortical Tubules in Response to Phospholipase A2 from Russell’s Viper Venom.
Poster for 2016 The ASN Kidney Week,
Chicago, USA
2016
Limbutara K, Somparn P, Pakmanee N, Chanhome L, Khow O, Chaiyabutr N, Sitprija V, Praditpornsilpa K, Pisitkun T.
Please Mind The Gap: The New Anion Gap Reference Values for Classification of Metabolic Acidosis.
Poster for 2016 Annual meeting of the Royal College of Physician of Thailand
Pattaya, Thailand
2016
Limbutara K, Katavetin P, Eiam-Ong S, Praditpornsilpa K.
Honors and awards
Fellowship Investigator Award, the Nephrology Society of Thailand
N/A
N/A
2016
Highest score in the Thai board of internal medicine examination
N/A
N/A
2013
Outstanding Internal Medicine Resident award, Hatyai Hospital
N/A
N/A
2013
Highest score in the Thai national medical competency assessment examination (Clinical science)
N/A
N/A
2009
Educational awards for achieving the highest score in 7 classes
N/A
N/A
2004-2008
- Cell Biology
- Neuroscience
- Medical Physiology
- Principle of Pathology
- Principle of Pharmacology
- General Surgery
- Evidence-based Medicine